A number of studies have been done on large-flowered fiddleneck. These include cryptic self-incompatibility (Weller and Ornduff 1977), nutlet production and germination (Pavlik 1988), pollen tube growth and inbreeding depression (Weller and Ornduff 1991), a reintroduction effort in 1989 (Pavlik et al. 1993), morph parenthood and nutlet yield (Espeland and Carlsen 1995), effects on germination (Carlsen and Gregory 1995), competition between Amsinckia grandiflora and grasses (Carlsen and Menke 1995), and reducing competitive suppression (Carlsen et al. 2000).

A number of studies have been done on large-flowered fiddleneck. These include cryptic self-incompatibility (Weller and Ornduff 1977), nutlet production and germination (Pavlik 1988), pollen tube growth and inbreeding depression (Weller and Ornduff 1991), a reintroduction effort in 1989 (Pavlik et al. 1993), morph parenthood and nutlet yield (Espeland and Carlsen 1995), effects on germination (Carlsen and Gregory 1995), competition between Amsinckia grandiflora and grasses (Carlsen and Menke 1995), and reducing competitive suppression (Carlsen et al. 2000).

Based on an August 2020 extract of the California Plant Rescue Database, University of California Botanical Garden has collected 4 seed accessions of Amsinckia grandiflora from 3 plant occurrences listed in the California Natural Diversity Database. These collections together emcompass an unknown number of maternal plants

Amsinckia grandiflora is only known from 8 sites historically, 5 of which are either extirpated or poor introductions. The 3 extant sites occur on LL lab property and on private land. Only a little over 3000 plants come up in all sites in any given year. None are in permanent protection with management for weed control and grazing control.

Threats include (as stated by USFWS 1997): Non-native plants Agriculture Development Grazing Possibly by altered fire frequency

There are two populations on Lawrence Livermore National Laboratory (LLNL) property: 1 population has between 23-400 individuals and the other has < 29 individuals. Another population of thousands of individuals on private land was recently discovered not far from the LLNL populations. An ex situ population has been established within the historic range at Black Diamond Mines Regional Preserve in Contra Costa Co.

A number of studies have been done on large-flowered fiddleneck. These include cryptic self-incompatibility (Weller and Ornduff 1977), nutlet production and germination (Pavlik 1988), pollen tube growth and inbreeding depression (Weller and Ornduff 1991), a reintroduction effort in 1989 (Pavlik et al. 1993), morph parenthood and nutlet yield (Espeland and Carlsen 1995), effects on germination (Carlsen and Gregory 1995), competition between Amsinckia grandiflora and grasses (Carlsen and Menke 1995), and reducing competitive suppression (Carlsen et al. 2000).

The U.S. Department of Energy, the U.S. Fish & Wildlife Service, and the California Department of Fish & Game established the 160-acre Amsinckia grandiflora Reseve on the Site 300 Experimental Test Facility of the Lawrence Livermore National Laboratory in April 2000. The populations in this reserve are monitored by the staff ecologist at LLNL.

Studies are needed to evaluate all the impacts (trampling, soil compaction, herbivory) as well as the benefits (increased habitat patchiness) of using livestock to favor native herbs over introduced annual grasses. The effective management of introduced competitors will be critical to successful reintroductions of large-flowered fiddleneck. Additional trials are needed to determine the range of species, habitats, and land-use situations in which herbicides could be used safely, responsibly, and effectively to meet conservation objectives (Pavlik et al. 1993). Long-term monitoring of the ex situ population at Black Diamond Mines Regional Preserve is needed to confirm the success of this introduction.

Seeds are needed for long-term storage.